Interleukin-27, an Anti-HIV-1 Cytokine, Inhibits Replication of Hepatitis C Virus
نویسندگان
چکیده
منابع مشابه
Interleukin-1 inhibits hepatitis C virus subgenomic RNA replication by activation of extracellular regulated kinase pathway.
Interleukin-1 (IL-1) plays an important role in the inflammatory process. Some studies have demonstrated that IL-1 production was impaired in patients with chronic infections of hepatitis C virus (HCV), implying that IL-1 may play a role in viral clearance. Using an HCV subgenomic replicon cell line, we demonstrate that IL-1 can effectively inhibit HCV subgenomic RNA replication and viral prote...
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Postmenopausal women with chronic hepatitis C exhibited a poor response to interferon (IFN) therapy compared to premenopausal women. Osteoporosis is the typical complication that occurs in postmenopausal women. Recently, it was reported that an osteoporotic reagent, vitamin D3, exhibited anti-hepatitis C virus (HCV) activity. Therefore, we investigated whether or not another osteoporotic reagen...
متن کاملReplication of hepatitis C virus.
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Objective: Influenza virus, which is associated with high level of morbidity and mortality, has been recently considered a public health concern; however, the methods of choice to control and treat it are limited. Our previous study showed anti-influenza virus activity of pomegranate peel extract (PPE). In this study, the mechanism through which PPE acts against influenza virus...
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conclusions lrrfip1 and its mediated production of type i interferon play a role in controlling hcv infection. the findings of this study provide new target for hcv treatment and contribute to development of anti-hcv drugs. results lrrfip1 increased the expression of ifn-β in hepatocytes with or without hcv infection. induction of ifn-β by lrrfip1 was enhanced with the presence of hepatitis c v...
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ژورنال
عنوان ژورنال: Journal of Interferon & Cytokine Research
سال: 2010
ISSN: 1079-9907,1557-7465
DOI: 10.1089/jir.2009.0093